Biochem/physiol Actions

Cell permeable: no

Reversible: no

Primary TargetA negative control for Phorbol-12,13-didecanoate (PDD) and Phorbol-12-myristate-13-acetate (PMA)

Product does not compete with ATP.

General description

Inactive on mouse skin as an inflammatory and tumor-promoting agent. Useful as a negative control for Phorbol-12,13-didecanoate (PDD; Cat. No. 524392) and Phorbol-12-myristate-13-acetate (PMA; Cat. No. 524400).

Reported to be inactive on mouse skin as an inflammatory and tumor-promoting agent. Used as a negative control for phorbol-12,13-didecanoate (PDD, Cat. No. 524392) and phorbol-12-myristate-13-acetate (PMA, Cat. No. 524400).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Akiguchi, I., et al. 1993. Endocrinology 138, 379.Clarke, B.L., et al. 1993. Endocrinology132, 1168.Natarajan, V. and Garcia, J.G. 1993. J. Lab. Clin. Med.121, 337.Slomiany, B.L., et al. 1992. J. Physiol. Pharmacol.43, 223.

Packaging

Packaged under inert gas

1, 5 mg in Alu drum

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 6 months at -20°C.

Warning

Toxicity: Highly Toxic (H)